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TRP 1.02 Bacterial: Febris recurrens/relapsing fever (Borrelia recurrentis, Borrelia duttoni)

Content version
U-40.2
Updated
10/20/2025 - 12:38

Recommendations

≥ 18 years
Dosage Remarks
benzylpenicillin IV 1 million IU single dose

followed by

doxycycline PO 200 mg single dose

Borrelia recurrentis (louse-borne)
doxycycline PO 100 mg twice daily for 14 to 21 days

or

amoxicillin PO 500 mg three times daily for 14 to 21 days

or

ceftriaxone IV 2000 mg once daily for 14 to 21 days

Borrelia duttoni (tick-borne)

Comments

febris recurrens = relapsing fever

Cave: Jarisch-Herxheimer reaction