Recommendations
| Dosage | Remarks | |
|---|---|---|
|
benzylpenicillin IV 2 million IU 6 times daily
+ clindamycin IV 600 mg 3 times daily+ amikacin IV 20 mg/kg once daily |
Unknown pathogen Consider administration of immunoglobulin in consultation with a medical microbiologist/infectious disease specialist |
|
|
benzylpenicillin IV 2 million IU 6 times daily for at least 7 days
+ clindamycin IV 600 mg 3 times daily for at least 7 days |
Group A streptococcus (toxic strep) Consider administration of immunoglobulin in consultation with a medical microbiologist/infectious disease specialist |
|
|
amoxicillin + clavulanic acid IV 1000/200 mg 4 times daily
+ amoxicillin IV 1000 mg 2 times daily+ amikacin IV 20/20 mg/kg once daily |
Type 1 (aerobic and anaerobic mixed flora, streptococci) |
| Dosage | Remarks | |
|---|---|---|
|
cefuroxime IV 1500 mg 3 times daily
+ clindamycin IV 600 mg 3 times daily+ amikacin IV 20 mg/kg once daily |
Unknown pathogen If NO anaphylactic reaction to penicillins. Consider administration of immunoglobulin in consultation with a medical microbiologist/infectious disease specialist |
|
|
cefuroxime IV 1500 mg 3 times daily
+ clindamycin IV 600 mg 3 times daily |
Group A streptococcus (toxic strep) If NO anaphylactic reaction to penicillins. Consider administration of immunoglobulin in consultation with a medical microbiologist/infectious disease specialist |
|
|
cefuroxime IV 1500 mg 3 times daily
+ clindamycin IV 600 mg 3 times daily+ amikacin IV 20 mg/kg once daily |
Type 1 (aerobic and anaerobic mixed flora, streptococci) If NO anaphylactic reaction to penicillins. |
*See protocol Policy for allergy to antibiotics | Radboud UMC
Surgical treatment required