Recommendations
| Дозування | Ремарки | |
|---|---|---|
|
piperacillin/tazobactam IV continuous infusion per 24 hours for 5 days
or piperacillin/tazobactam IV 4000/500 mg 4 times daily for 5 days |
Dosing for continuous infusion: First administer a loading dose of 4000/500 mg over 30 minutes, then 16000/2000 mg continuous infusion per 24 hours. |
| Дозування | Ремарки | |
|---|---|---|
|
cefuroxime IV 1500 mg 3 times daily
+ metronidazole PO 500 mg 3 times daily+ amikacin IV 20 mg/kg single dose |
non-IgE-mediated penicillin allergy amikacin until culture results are known |
*See protocol Policy for antibiotic allergy | Radboud UMC
Duration depends on the clinical situation. There is evidence that 4 days of antibiotic treatment after achieving source control is sufficient (Sawyer et al. NEJM 2015)