Recommendations
| Дозування | Ремарки | |
|---|---|---|
|
piperacillin/tazobactam IV continuous over 24 hours
or piperacillin/tazobactam IV 4500 mg 4 times daily |
Dosing for continuous infusion: Initially load with 4000/500 mg over 30 minutes, then 16000/2000 mg continuously over 24 hours. |
| Дозування | Ремарки | |
|---|---|---|
|
cefuroxime IV 1500 mg 3 times daily
+ metronidazole PO 500 mg 3 times daily+ amikacin IV 20 mg/kg once |
non–IgE-mediated penicillin allergy amikacin only in case of sepsis |
*See protocol Policy for antibiotic allergy | Radboud UMC
Do not routinely treat patients with uncomplicated acute diverticulitis (Hinchey 1) with antibiotics.
Duration depends on the clinical situation. There is evidence that 4 days of antibiotic treatment after achieving source control is sufficient (Sawyer et al. NEJM 2015).
Amikacin in case of sepsis until culture results are known.