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Recommendations

≥ 18 years
Дозування Ремарки
piperacillin/tazobactam iv continuous infusion over 24 hours

or

piperacillin/tazobactam iv 4000/500 mg 4 times daily

Dosing for continuous infusion:

Initially load with 4000/500 mg over 30 minutes, then 16000/2000 mg continuous over 24 hours.

≥ 18 years

Contraindications: Allergy to penicillins*

Дозування Ремарки
cefuroxime iv 1500 mg 3 times daily

+

amikacin iv 20 mg/kg single dose

for non–IgE-mediated penicillin allergy

amikacin is only added in the case of sepsis

cefuroxime iv 1500 mg 3 times daily

metronidazole po 500 mg 3 times daily

In the case of a bilio-digestive anastomosis

Comments

after adequate drainage of the biliary tract: maximum treatment duration 3 days