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Recommendations

≥ 18 years
Дозування Ремарки
valaciclovir p.o. 500 mg twice daily for 5 days

or

aciclovir p.o. 400 mg three times daily for 5 days

or

famciclovir p.o. 250 mg three times daily for 5 days

SWAB remarks

Primary infection

valaciclovir p.o. 1000 mg twice daily for 10 days

or

aciclovir p.o. 800 mg three times daily for 10 days

or

famciclovir p.o. 500 mg three times daily for 10 days

SWAB remarks

Primary infection in immunocompromised adults; treat until lesion re-epithelialisation

valaciclovir p.o. 500 mg twice daily for 5 days

or

aciclovir p.o. 400 mg three times daily for 5 days

or

famciclovir p.o. 125 mg twice daily for 5 days

SWAB remarks

Recurrent infection in immunocompetent and immunocompromised adults

valaciclovir p.o. 500 mg twice daily for 3 days

or

aciclovir p.o. 800 mg three times daily for 2 days

or

famciclovir p.o. 1000 mg twice daily for 1 day

SWAB remarks

Frequent recurrences in immunocompetent adults

valaciclovir p.o. 500 mg once daily

or

valaciclovir p.o. 1000 mg once daily

or

aciclovir p.o. 400 mg twice daily

or

famciclovir p.o. 250 mg twice daily

SWAB remarks

Prophylaxis for recurrent episodes (>6 recurrences per year); maximum 1 year

Comments

Primary anogenital HSV infection in pregnancy 

- aciclovir p.o. 400 mg, three times daily for 5 days;
- valaciclovir p.o. 500 mg, twice daily for 5 days

Refer all primary and recurrent infections during pregnancy to a gynaecologist!