Recommendations
| Дозування | Ремарки | |
|---|---|---|
|
flucloxacillin IV loading dose 1 g, 6 g continuous over 24 hours
or cefazolin IV loading dose 1 g, 6 g continuous over 24 hours |
Post-operatively pending culture results.
If continuous infusion is not possible: then flucloxacillin 6 times daily 1 gram or cefazolin 3 times daily 2 grams |
|
|
flucloxacillin IV loading dose 2 g, 12 g continuous over 24 hours
+ ceftazidime IV 2000 mg three times daily |
When severely ill, with a haematogenous source and/or recent cultures showing gram-negative pathogens (both in the setting of revision and no revision) in consultation with the medical microbiologist/infectiologist |
|
|
teicoplanin IV
|
In the case of revision surgery post-operatively pending culture results For loading and maintenance dosing, see teicoplanin |
Goal: surgical debridement with the aim of retaining the prosthesis/osteosynthesis material (DAIR: debridement, antibiotics, implant retention).
Adjust antibiotics according to culture results in consultation with the microbiologist/infectiologist.
In recurrent infection of an in situ prosthesis/osteosynthesis material: consult the microbiologist/infectiologist regarding antibiotic management based on previous cultures.
Each patient should, in principle, be discussed at the multidisciplinary orthopaedics-infection meeting on Wednesday mornings. Register via the orthopaedics ward doctor.
Consider postoperative wound infection as infection of prosthetic material