Recommendations
| Дозування | Ремарки | |
|---|---|---|
|
flucloxacillin IV 6 g/24 h
|
Loading dose 1 gram flucloxacillin bolus, then continuous infusion (If continuous infusion is not possible, give flucloxacillin 1 g six times daily) |
|
|
flucloxacillin IV 6 g/24 h
+ amikacin IV 20 mg/kg once daily |
In sepsis Loading dose 1 gram flucloxacillin bolus, then continuous infusion (If continuous infusion is not possible, give flucloxacillin 1 g six times daily) |
|
|
cefuroxime IV 1500 mg three times daily
|
When a Gram-negative pathogen is suspected, but no sepsis |
| Дозування | Ремарки | |
|---|---|---|
|
cefazolin IV 2000 mg three times daily
|
Non-severe penicillin allergy |
|
|
clindamycin IV 600 mg three times daily
|
Severe beta-lactam allergy |
*See protocol Policy for antibiotic allergy | Radboud UMC
Total duration of treatment for uncomplicated cases: 4 weeks.
Adjust antibiotics according to culture results where possible.
The switch to oral therapy depends on culture results, clinical response and the presence or absence of bacteraemia.