Recommendations
| Dosage | Remarks | |
|---|---|---|
|
amoxicillin + clavulanic acid oral 625 mg three times daily for 10 days
|
For early mastoiditis |
|
|
amoxicillin + clavulanic acid IV 1200 mg four times daily for 10 days
|
For extensive disease and/or if severely ill |
In case of allergy: see Policy for antibiotic allergy | Radboud UMC
In combination with surgery
If necessary, adjust antibiotic therapy according to culture results, in consultation with a medical microbiologist/infectiologist
If intracranial complications or extracranial abscess formation are confirmed, see antibiotic policy for CNS 3.01 brain abscess - unknown pathogen