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Recommendations

≥ 18 years

Indications: Entercytozoon bieneusi

Dosage Remarks

No proven effective therapy, see remarks

In immunocompromised patients possibly fumagillin 20mg three times daily for 14 days 

≥ 18 years

Indications: Encephalitozoon intestinalis

Dosage Remarks
albendazole PO 400 mg twice daily for 21 to 28 days

First choice

Comments

Infection usually occurs only in severely immunocompromised patients. The preferred treatment is to restore immune function as much as possible. 

Fumagillin is not yet available in the Netherlands 

Severe bone marrow toxicity (neutropenia, thrombocytopenia) has been reported with fumagillin 

Use of albendazole during pregnancy and breastfeeding: probably safe during pregnancy (2nd and 3rd trimester) and breastfeeding

Take albendazole with a fatty meal (increased absorption).