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Recommendations

≥ 18 years
Dosage Remarks
cefazolin IV single dose

+

metronidazole IV 500 mg single dose

hysterectomy

cefazolin IV single dose

+

metronidazole IV 500 mg single dose

surgical treatment of vulval carcinoma

inguinal lymph node dissection: no prophylaxis

low-risk laparoscopy *see note: no prophylaxis

cefazolin IV single dose

high-risk laparoscopy *see note. In case of bowel injury also metronidazole IV 500 mg

cefazolin IV single dose

gynaecological surgery with implant or non-absorbable sutures; when opening the vagina also metronidazole 500 mg IV single dose

vaginal surgery without implant, including anterior and posterior repair: no prophylaxis

cefazolin IV single dose

+

metronidazole IV 500 mg single dose

mid-compartment prolapse surgery

azithromycin PO 1000 mg single dose

instrumental abortion in the 1st trimester; no prophylaxis for miscarriage curettage

cefazolin IV 2000 mg single dose

primary caesarean section, to be administered before incision

cefazolin IV 2000 mg single dose

+

metronidazole IV 500 mg single dose

secondary or emergency caesarean section, to be administered before incision if possible

For code Red caesarean section give a second dose of cefazolin if necessary

cefazolin IV 1 g single dose

+

metronidazole IV 500 mg single dose

3rd/4th degree rupture (OASIS)

extended prophylaxis 3 days amoxicillin/clavulanic acid 3 times daily 500/125 mg

placenta removal (manual): no prophylaxis

cefazolin IV 2 g single dose

+

metronidazole IV 500 mg single dose

neovagina

extended prophylaxis 7 days amoxicillin/clavulanic acid 3 times daily 500/125 mg

Dilatation-indicated transvaginal cerclage (emergency cerclage):

2 weeks extended prophylaxis amoxicillin-clavulanic acid 1000/100 mg 4 times daily for 2 weeks

cefazolin IV 1000 mg single dose

History-indicated transvaginal cerclage

Ultrasound-indicated transvaginal cerclage

 

cefazolin IV 2 g single dose

Transabdominal cerclage

≥ 18 years

Indication: In case of cephalosporin allergy

Dosage Remarks
clindamycin IV 600 mg single dose

hysterectomy

clindamycin IV 600 mg single dose

primary and secondary caesarean section

Comments

A laparoscopy with low infection risk is defined as: a short (< 1 hour) procedure that proceeds uncomplicatedly, in a patient under 70 years, with no spillage of cyst contents, with limited blood loss (< 500 ml), and in which no implant, mesh or other non-absorbable material is used.

In all other cases the procedure is considered a laparoscopy with higher infection risk.