Recommendations
| Dosage | Remarks | |
|---|---|---|
|
amoxicillin oral 1000 mg twice daily for 10 to 14 days
+ clarithromycin oral 500 mg twice daily for 10 to 14 days |
SWAB remarks with a proton pump inhibitor twice daily |
| Dosage | Remarks | |
|---|---|---|
|
clarithromycin oral 500 mg twice daily for 14 days
+ metronidazole oral 500 mg twice daily for 14 days |
SWAB remarks with a proton pump inhibitor twice daily |
| Dosage | Remarks | |
|---|---|---|
|
tetracycline oral 500 mg four times daily for 14 days
+ metronidazole oral 500 mg three times daily for 14 days |
SWABID (National) remarks plus bismuth 120 mg four times daily and a proton pump inhibitor twice daily |
|
|
amoxicillin oral 1000 mg three times daily for 14 days
+ metronidazole oral 500 mg three times daily for 14 days |
SWAB remarks with a proton pump inhibitor twice daily |
Continue the proton pump inhibitor once daily (!) for 4 weeks following the eradication course
Choice of antibiotic regimen depends on whether the local prevalence of resistance to clarithromycin and/or metronidazole is below or above 15%
If the first eradication attempt fails, base the second regimen on resistance testing results
Bismuth (bismuth subcitrate) is no longer registered in the Netherlands, but Radboud has an import licence from the IGJ for the indication mentioned above. It is therefore available, but a physician's declaration is required.