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Prophylaxis for HIPEC

Content version
U-23.2
Updated
10/20/2025 - 13:34

Recommendations

≥ 18 years
Dosage Remarks
cefazolin IV 2000 mg

+

metronidazole IV 500 mg

Comments

If the operation lasts longer than 4 hours from incision: repeat cefazolin. There is no indication for prolonged prophylaxis.