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CMV retinitis

Content version
U-226.2
Updated
10/20/2025 - 15:18

Recommendations

≥ 18 years
Dosage Remarks
1st choice
valganciclovir oral (PO) 900 mg twice daily for at least 14 days

SWAB remarks

Mild cases
1st choice alternative
ganciclovir IV 5 mg/kg twice daily for at least 14 days
2nd choice
foscarnet IV 90 mg/kg twice daily for at least 14 days

Comments

If the macula is involved: ganciclovir IV + intravitreal ganciclovir injection: initial injection is 4 mg/0.1 mL, follow-up injections are 2 mg/0.1 mL until clinical remission.

If resistant to ganciclovir: foscarnet IV + intravitreal foscarnet injection 2.4 mg/0.1 mL.

Secondary prophylaxis after treatment: 

  • valganciclovir oral (PO) 900 mg once daily for at least 3 months
  • If resistant to ganciclovir: consult regarding secondary prophylaxis and consider foscarnet IV 90 mg/kg once daily