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Recommendations

≥ 18 years
Dosage Remarks
1st choice
amoxicillin IV 12 g/24 h in divided doses
2nd choice
teicoplanin IV

loading and maintenance dosing, see teicoplanin | Radboud UMC

≥ 18 years

Indications: oral switch

Dosage Remarks
1st choice
amoxicillin PO 1000 mg 4 times daily
2nd choice
linezolid PO 600 mg twice daily

Comments

Start treatment when susceptibility is confirmed

Treat intravenously for at least 2 weeks. Switch to oral therapy guided by cultures and the clinical picture.

Linezolid maximum 4 weeks because of neuropathy/cytopenia, weekly full blood count monitoring required