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Recommendations

≥ 18 years
Dosage Remarks

Diagnostic angiography, PTA, placement of metallic stent and brachiocephalic procedures without implantation of prosthetic material; no prophylaxis

cefazolin IV 2 g single dose

Vascular prosthesis (including endograft) and peripheral bypass

cefazolin IV 2 g single dose

Amputation

≥ 18 years

Indications: Allergy

Dosage Remarks
clindamycin IV 600 mg single dose

or

vancomycin IV 1000 mg single dose

strong suspicion of or proven cefazolin allergy or a previous severe ‘delayed-type’ allergy to a ß-lactam antibiotic

Comments

If necessary, a second dose for an operation lasting > 4 hours and/or in case of significant blood loss during the operation