MYC 1.4 Candida: Abdominal candidiasis

Content version: U-114.2
Updated: 10/20/2025 - 12:33

Recommendations

≥ 18 years
	Dosage	Remarks
1st choice	anidulafungin iv loading dose 200 mg, then 100 mg once daily or caspofungin iv loading dose 70 mg, then 50 mg once daily or micafungin iv 100 mg once daily	Invasive abdominal candidiasis/peritonitis irrespective of species and azole susceptibility, (except invasive Candida urinary tract infection)

≥ 18 years

Indications: for resistance or intolerance to echinocandins
	Dosage	Remarks
2nd choice	liposomal amphotericin B (Ambisome) iv 3 mg/kg once daily	Invasive abdominal candidiasis/peritonitis irrespective of species and azole susceptibility, (except invasive Candida urinary tract infection)

≥ 18 years

Indications: Step-down
	Dosage	Remarks
	oral fluconazole loading dose 800 mg, then 400 mg once daily for a minimum of 2 weeks	Step down after initial treatment ≥5 days with an echinocandin: In patients with clinical improvement, haemodynamically stabilised patients, drainage of all infected foci, and demonstrated fluconazole susceptibility. Not for C. glabrata, C. krusei, or in patients with intravascular or prosthesis-associated candidiasis

Comments

Source control (debridement and drainage of all infected foci) is essential.

Duration of treatment depends on the surgical and radiological resolution of infected foci.